Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 5/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | FLT4 | P35916 | 1/20 | 0.39 |
| ▸ | ATAD2 | Q6PL18 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | EED | O75530 | 2/20 | 0.36 |
| ▸ | SUZ12 | Q15022 | 2/20 | 0.36 |
| ▸ | EZH2 | Q15910 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2750730 | 0.87 | ALDH1A1 (0.57) | KDM4EALDH1A1HPGDHSD17B10KDR | |
| SCHEMBL2804195 | 0.83 | ALDH1A1 (0.42) | KDM4EALDH1A1HPGDHSD17B10TP53 | |
| SCHEMBL11157418 | 0.80 | KDR (0.42) | KDM4EALDH1A1HPGDHSD17B10KDR | |
| SCHEMBL23176187 | 0.72 | KDM4E (0.36) | KDM4EALDH1A1HPGDHSD17B10KDR | |
| SCHEMBL18878946 | 0.69 | HTT (0.38) | KDM4EALDH1A1HPGDHSD17B10ADORA2A | |
| SCHEMBL8795590 | 0.69 | KDM4E (0.50) | KDM4EALDH1A1HPGDHSD17B10TP53 | |
| SCHEMBL24548242 | 0.69 | HTT (0.38) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL31679754 | 0.69 | HTT (0.46) | KDM4EALDH1A1HPGDHSD17B10NPC1 | |
| SCHEMBL2589970 | 0.69 | KDR (0.48) | ALDH1A1HPGDHSD17B10JAK2KDR | |
| SCHEMBL23143318 | 0.67 | JAK2 (0.46) | JAK2TP53PKMKDRFLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021058595-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2021-04-01 | — | — | WO | disclosed |
| WO-2021058595-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2021-04-01 | — | — | WO | disclosed |
| EP-1691811-A1 | COMBINATION OF A SEDATIVE AND A NEUROTRANSMITTER MODULATOR, AND METHODS FOR IMPROVING SLEEP QUALITY AND TREATING DEPRESSION | Sepracor, Inc. (US) | 2006-08-23 | — | — | EP | disclosed |
| WO-2005060968-A1 | COMBINATION OF A SEDATIVE AND A NEUROTRANSMITTER MODULATOR, AND METHODS FOR IMPROVING SLEEP QUALITY AND TREATING DEPRESSION | SEPRACOR INC. (US) | 2005-07-07 | — | — | WO | disclosed |