Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6009749 | 0.87 | ADORA2A (0.45) | ADORA2A | |
| SCHEMBL6010438 | 0.84 | — | — | |
| SCHEMBL6009718 | 0.80 | — | — | |
| SCHEMBL5408729 | 0.77 | — | — | |
| SCHEMBL6009786 | 0.77 | ADORA2A (0.45) | ADORA2A | |
| SCHEMBL5418951 | 0.77 | — | — | |
| SCHEMBL5426300 | 0.76 | ADORA3 (0.54) | ADORA3ADORA2BADORA2AADORA1 | |
| SCHEMBL5418926 | 0.74 | ADORA3 (0.58) | ADORA3ADORA2BADORA2AADORA1 | |
| SCHEMBL6010331 | 0.73 | ADORA2A (0.45) | ADORA2A | |
| SCHEMBL5787999 | 0.70 | ADORA2A (0.57) | ADORA3ADORA2BADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1615930-A2 | TRIAZOLOTRIAZINES AND PYRAZOLOTRIAZINES USEFUL AS A2A ADENOSINE RECEPTOR ANTAGONISTS | Biogen Idec MA, Inc. (US) | 2006-01-18 | — | — | EP | disclosed |
| WO-2004092170-A2 | TRIAZOLOTRIAZINES AND PYRAZOLOTRIAZINES USEFUL AS A2A ADENOSINE RECEPTOR ANTAGON ISTS | BIOGEN IDEC MA INC. (US) | 2004-10-28 | — | — | WO | disclosed |