SCHEMBL5801697

SCHEMBL5801697

CC(C)(Sc1ccc(CCN2C(=O)c3ccccc3C2=O)cc1)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP3 P42574 2/20 0.52
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA4 P22748 1/20 0.48
CA9 Q16790 1/20 0.48
RAB9A P51151 3/20 0.47
ALDH1A1 P00352 2/20 0.47
MAPT P10636 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
KDM4E B2RXH2 1/20 0.47
GAA P10253 1/20 0.47
MMP2 P08253 3/20 0.47
MMP9 P14780 3/20 0.47
NPC1 O15118 2/20 0.46
MEN1 O00255 1/20 0.46
POLB P06746 1/20 0.46
KMT2A Q03164 1/20 0.46
TAAR1 Q96RJ0 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3885465 0.85 CASP3 (0.45) CASP3CA1CA2CA4CA9
SCHEMBL29724090 0.75 CASP3 (0.86) CASP3CA1CA2CA4CA9
SCHEMBL1142116 0.75 CASP3 (0.86) CASP3CA1CA2CA4CA9
SCHEMBL18074272 0.74 CASP3 (0.67) CASP3CA1CA2CA4CA9
SCHEMBL6358162 0.73 CASP3 (0.42) CASP3CA1CA2CA4CA9
SCHEMBL29452096 0.73 GAA (0.50) CASP3CA1CA2CA4CA9
SCHEMBL1430310 0.73 CASP3 (0.65) CASP3CA1CA2CA4CA9
SCHEMBL1065287 0.73 CASP3 (0.65) CASP3CA1CA2CA4CA9
Dimethylamine SCHEMBL4418548 0.73 CASP3 (0.75) CASP3CA1CA2CA4CA9
SCHEMBL20822286 0.72 CASP3 (0.56) CASP3CA1CA2CA4CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006080652-A1 PROCESS FOR PREPARING THE INTERMEDIATE COMPOUNDS FOR PPARALPHA LIGANDS KANG HEONJOONG (KR) 2006-08-03 WO disclosed