Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | ACACA | Q13085 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.32 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | CPT2 | P23786 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5802319 | 0.86 | — | — | |
| SCHEMBL15158161 | 0.81 | ACACB (0.35) | ACACBACACAFFAR1CPT2TDP1 | |
| SCHEMBL996508 | 0.78 | ALDH1A1 (0.39) | ALDH1A1PIK3CDACACBACACAMEN1 | |
| SCHEMBL13384035 | 0.78 | BLM (0.52) | ALDH1A1PIK3CDACACBACACACA2 | |
| SCHEMBL16357610 | 0.78 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2AKDM4EKCNH3 | |
| SCHEMBL81885 | 0.78 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2AKDM4EKCNH3 | |
| SCHEMBL19480690 | 0.77 | CA1 (0.38) | ALDH1A1PIK3CDACACBACACAMEN1 | |
| SCHEMBL8414663 | 0.76 | ALDH1A1 (0.47) | ALDH1A1ACACBACACAMEN1KMT2A | |
| SCHEMBL9067505 | 0.76 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2AKDM4EKCNH3 | |
| SCHEMBL10749460 | 0.76 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2AKDM4EKCNH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006060885-A1 | 7-(2-CYCLOHEXYLIDENE-ETHYLIDENE)-SPIRO[5.5]UNDECANES USEFUL FOR MAKING PHARMACEUTICAL COMPOSITIONS | K.U.LEUVEN RESEARCH & DEVELOPMENT (BE) | 2006-06-15 | — | — | WO | disclosed |