Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 12/20 | 0.69 |
| ▸ | RAD52 | P43351 | 3/20 | 0.67 |
| ▸ | DRD2 | P14416 | 3/20 | 0.66 |
| ▸ | DRD1 | P21728 | 3/20 | 0.66 |
| ▸ | HRH1 | P35367 | 3/20 | 0.66 |
| ▸ | DRD3 | P35462 | 3/20 | 0.66 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.66 |
| ▸ | DRD5 | P21918 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 6/20 | 0.65 |
| ▸ | MAPT | P10636 | 6/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.65 |
| ▸ | TP53 | P04637 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.65 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.65 |
| ▸ | HTR1A | P08908 | 2/20 | 0.65 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.65 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5803456 | 1.00 | FPR2 (0.69) | FPR2RAD52DRD2DRD1HRH1 | |
| Fluphenazine Decanoate SCHEMBL29563075 | 1.00 | FPR2 (0.69) | FPR2RAD52DRD2DRD1HRH1 | |
| SCHEMBL5801488 | 1.00 | FPR2 (0.69) | FPR2RAD52DRD2DRD1HRH1 | |
| Fluphenazine Enanthate SCHEMBL29389566 | 1.00 | FPR2 (0.69) | FPR2RAD52DRD2DRD1HRH1 | |
| Fluphenazine Decanoate SCHEMBL41288 | 1.00 | FPR2 (0.69) | FPR2RAD52DRD2DRD1HRH1 | |
| Fluphenazine Enanthate SCHEMBL120793 | 1.00 | FPR2 (0.69) | FPR2RAD52DRD2DRD1HRH1 | |
| SCHEMBL5802453 | 1.00 | FPR2 (0.69) | FPR2RAD52DRD2DRD1HRH1 | |
| SCHEMBL5800312 | 1.00 | FPR2 (0.69) | FPR2RAD52DRD2DRD1HRH1 | |
| Fluphenazine Decanoate SCHEMBL3714532 | 0.99 | FPR2 (0.68) | FPR2RAD52DRD2DRD1HRH1 | |
| Fluphenazine Decanoate SCHEMBL15533373 | 0.99 | FPR2 (0.68) | FPR2RAD52DRD2DRD1HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006058199-A1 | METHODS OF MODULATING HIGH-DENSITY LIPOPROTEIN CHOLESTEROL LEVELS AND PHARMACEUTICAL FORMULATIONS FOR THE SAME | FAZIX CORPORATION (US) | 2006-06-01 | — | — | WO | disclosed |
| US-20060111346-A1 | Methods of modulating high-density lipoprotein cholesterol levels and pharmaceutical formulations for the same | FAZIX CORPORATION. | 2006-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060111346-A1 | Methods of modulating high-density lipoprotein cholesterol levels and pharmaceutical formulations for the same | HDLBP, LDLR, CETP | FPR2 1313/4885RAD52 2967/4885DRD2 1187/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.