Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29657743 | 0.79 | SIGMAR1 (0.54) | SIGMAR1L3MBTL1ALDH1A1KMT2ACYP1A2 | |
| SCHEMBL14461587 | 0.79 | SIGMAR1 (0.54) | SIGMAR1L3MBTL1ALDH1A1KMT2ACYP1A2 | |
| SCHEMBL517207 | 0.79 | SIGMAR1 (0.54) | SIGMAR1L3MBTL1ALDH1A1KMT2ACYP1A2 | |
| Bromide SCHEMBL7412701 | 0.78 | SIGMAR1 (0.53) | SIGMAR1L3MBTL1ALDH1A1KMT2ACYP1A2 | |
| SCHEMBL29862183 | 0.78 | SIGMAR1 (0.57) | SIGMAR1L3MBTL1ALDH1A1KMT2ACYP1A2 | |
| Hydrochloric Acid SCHEMBL4747710 | 0.78 | SIGMAR1 (0.53) | SIGMAR1L3MBTL1ALDH1A1KMT2ACYP1A2 | |
| SCHEMBL3232376 | 0.78 | SIGMAR1 (0.57) | SIGMAR1L3MBTL1ALDH1A1KMT2ACYP1A2 | |
| SCHEMBL19775768 | 0.77 | SIGMAR1 (0.59) | SIGMAR1ALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL23791095 | 0.76 | SIGMAR1 (0.52) | SIGMAR1ALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL3637274 | 0.76 | SIGMAR1 (0.51) | SIGMAR1L3MBTL1ALDH1A1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006059347-A2 | IMPROVED PROCESS FOR PREPARATION OF RAMIPRIL | MOREPEN LABORATORIES LIMITED (IN) | 2006-06-08 | — | — | WO | disclosed |