Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 4/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 11/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 8/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5816976 | 0.89 | FGFR1 (0.59) | FGFR1CYP3A4CYP2D6 | |
| SCHEMBL5803012 | 0.85 | FGFR1 (0.54) | FGFR1CYP3A4CYP2D6POLB | |
| SCHEMBL5802198 | 0.82 | FGFR1 (0.71) | FGFR1CYP3A4CYP2D6 | |
| SCHEMBL5803172 | 0.75 | FGFR1 (0.38) | FGFR1 | |
| SCHEMBL97302 | 0.74 | FGFR1 (1.00) | FGFR1CYP3A4CYP2D6 | |
| SCHEMBL16062936 | 0.73 | FGFR1 (0.69) | FGFR1POLB | |
| SCHEMBL12964220 | 0.73 | FGFR1 (0.69) | FGFR1POLB | |
| SCHEMBL16518408 | 0.73 | LPAR3 (0.58) | FGFR1CYP3A4 | |
| SCHEMBL17617674 | 0.72 | FGFR1 (0.69) | FGFR1CYP3A4CYP2D6POLB | |
| SCHEMBL5802194 | 0.71 | FGFR1 (0.40) | FGFR1CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006076015-A2 | 1-[2-(PHOSPHONOMETHOXY)ETHYL]-CYTOSINE AND ANALOGS THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2006-07-20 | — | — | WO | disclosed |