Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 7/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.44 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.40 |
| ▸ | EP300 | Q09472 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19470470 | 0.87 | FGFR1 (0.57) | FGFR1CYP3A4CYP2D6SLC22A6EP300 | |
| SCHEMBL139865 | 0.84 | FGFR1 (0.88) | FGFR1CYP3A4CYP2D6SLC22A6 | |
| SCHEMBL19470531 | 0.83 | FGFR1 (0.53) | FGFR1SLC22A6EP300 | |
| Brincidofovir SCHEMBL139922 | 0.83 | FGFR1 (1.00) | FGFR1CYP3A4CYP2D6SLC22A6 | |
| SCHEMBL22863226 | 0.83 | FGFR1 (1.00) | FGFR1CYP3A4CYP2D6SLC22A6 | |
| SCHEMBL19470239 | 0.83 | FGFR1 (0.53) | FGFR1CYP3A4CYP2D6SLC22A6EP300 | |
| Brincidofovir SCHEMBL12918810 | 0.83 | FGFR1 (1.00) | FGFR1CYP3A4CYP2D6SLC22A6 | |
| SCHEMBL19470297 | 0.83 | FGFR1 (0.53) | FGFR1SLC22A6 | |
| SCHEMBL5816976 | 0.82 | FGFR1 (0.59) | FGFR1CYP3A4CYP2D6EP300 | |
| SCHEMBL5803159 | 0.82 | FGFR1 (0.59) | FGFR1CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006076015-A2 | 1-[2-(PHOSPHONOMETHOXY)ETHYL]-CYTOSINE AND ANALOGS THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2006-07-20 | — | — | WO | disclosed |