Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | FAAH | O00519 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28969034 | 0.98 | NPC1 (0.63) | NPC1RAB9ASMN1; SMN2LMNAEPHX2 | |
| SCHEMBL27621693 | 0.98 | NPC1 (0.63) | NPC1RAB9ASMN1; SMN2LMNAEPHX2 | |
| SCHEMBL28105060 | 0.98 | NPC1 (0.63) | NPC1RAB9ASMN1; SMN2LMNAEPHX2 | |
| SCHEMBL8773507 | 0.98 | NPC1 (0.63) | NPC1RAB9ASMN1; SMN2LMNAEPHX2 | |
| SCHEMBL28969065 | 0.98 | NPC1 (0.63) | NPC1RAB9ASMN1; SMN2LMNAEPHX2 | |
| SCHEMBL29106946 | 0.98 | NPC1 (0.63) | NPC1RAB9ASMN1; SMN2LMNAEPHX2 | |
| SCHEMBL3806762 | 0.95 | EPHX2 (0.56) | NPC1RAB9ASMN1; SMN2LMNAEPHX2 | |
| SCHEMBL7422332 | 0.89 | HDAC1 (0.55) | LMNAEPHX2CYP3A4ALDH1A1 | |
| SCHEMBL10812443 | 0.87 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2LMNAEPHX2 | |
| SCHEMBL13387445 | 0.87 | FAAH (0.58) | NPC1RAB9ASMN1; SMN2LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006074261-A2 | METHOD AND COMPOSITIONS FOR CONTROLLING RELEASE OF ORGANIC COMPOSITIONS | MICHIGAN STATE UNIVERSITY (US) | 2006-07-13 | — | — | WO | disclosed |