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SCHEMBL5803471

SCHEMBL5803471

COc1ccc(C23Oc4cc(OC5OC(C(CO[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)COC5OC)cc(OC)c4C2(O)C(O)C(C(=O)O)C3c2ccccc2)cc1

nearest known ligand 0.68

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ EIF4A1 P60842 19/20 0.68
▸ CYP3A4 P08684 1/20 0.52
▸ HIF1A Q16665 1/20 0.52
▸ NFKB1 P19838 1/20 0.51
▸ RELA Q04206 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19666196 0.89 EIF4A1 (0.62) EIF4A1CYP3A4HIF1ANFKB1RELA
SCHEMBL19666198 0.89 EIF4A1 (0.62) EIF4A1CYP3A4HIF1ANFKB1RELA
SCHEMBL19666171 0.86 EIF4A1 (0.90) EIF4A1CYP3A4HIF1ANFKB1RELA
SCHEMBL19666228 0.86 EIF4A1 (0.90) EIF4A1CYP3A4HIF1ANFKB1RELA
SCHEMBL19666167 0.86 EIF4A1 (0.90) EIF4A1CYP3A4HIF1ANFKB1RELA
SCHEMBL19666234 0.86 EIF4A1 (0.90) EIF4A1CYP3A4HIF1ANFKB1RELA
SCHEMBL19666236 0.86 EIF4A1 (0.90) EIF4A1CYP3A4HIF1ANFKB1RELA
SCHEMBL19666231 0.86 EIF4A1 (0.90) EIF4A1CYP3A4HIF1ANFKB1RELA
SCHEMBL29958999 0.85 EIF4A1 (0.68) EIF4A1CYP3A4HIF1A
SCHEMBL22220113 0.81 EIF4A1 (0.90) EIF4A1CYP3A4HIF1ANFKB1RELA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006007634-A1 PROCESSES AND INTERMEDIATES CERYLID BIOSCIENCES LTD (AU) 2006-01-26 — — WO disclosed