SCHEMBL580377

SCHEMBL580377

CCC1=NCCCN1CC

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
INMT O95050 3/20 0.34
POLB P06746 1/20 0.34
USP2 O75604 1/20 0.33
LMNA P02545 1/20 0.33
TSHR P16473 1/20 0.33
TOP2A P11388 2/20 0.32
TOP2B Q02880 2/20 0.32
NOS3 P29474 1/20 0.31
NOS1 P29475 1/20 0.31
NOS2 P35228 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1831721 0.86
Hydrochloric Acid SCHEMBL7771939 0.84 TOP2A (0.42) TOP2ATOP2B
Bromide SCHEMBL28222949 0.84 TOP2A (0.40) INMTTOP2ATOP2B
SCHEMBL244993 0.83 POLB (0.33) INMTPOLBLMNATSHRTOP2A
SCHEMBL20469254 0.80 CYP1A2 (0.34) INMTPOLBLMNATSHR
SCHEMBL20037141 0.80 CYP2D6 (0.40) TSHR
SCHEMBL11686097 0.77 ALDH1A1 (0.37) INMTTSHR
SCHEMBL242327 0.76
SCHEMBL1312234 0.76
SCHEMBL10144705 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 186 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11225450-B2 Processes for preparing calixarenes SI GROUP, INC. (US) 2022-01-18 US claimed
US-20210047253-A1 PROCESSES FOR PREPARING CALIXARENES SI GROUP, INC. 2021-02-18 US claimed
EP-3768807-A1 COMPOSITION AND METHOD FOR PREVENTING OR REDUCING LOW SPEED PRE-IGNITION IN SPARK-IGNITED INTERNAL COMBUSTION ENGINES Chevron Oronite Company LLC (US) 2021-01-27 EP claimed
CN-112055742-A Composition and method for preventing or reducing low speed pre-ignition in spark-ignition internal combustion engines 雪佛龙奥伦耐有限责任公司 2020-12-08 CN claimed
WO-2020194041-A2 COMPOSITION AND METHOD FOR PREVENTING OR REDUCING LOW SPEED PRE-IGNITION IN SPARK-IGNITED INTERNAL COMBUSTION ENGINES CHEVRON ORONITE COMPANY LLC (US) 2020-10-01 WO claimed
US-10781154-B2 Processes for preparing calixarenes SI GROUP, INC. (US) 2020-09-22 US claimed
US-10640641-B2 Curable coating compositions of silane functional polymers KING INDUSTRIES (US) 2020-05-05 US claimed
US-20200062953-A1 CURABLE COATING COMPOSITIONS OF SILANE FUNCTIONAL POLYMERS KING INDUSTRIES 2020-02-27 US claimed
WO-2019180685-A1 COMPOSITION AND METHOD FOR PREVENTING OR REDUCING LOW SPEED PRE-IGNITION IN SPARK-IGNITED INTERNAL COMBUSTION ENGINES CHEVRON ORONITE COMPANY LLC (US) 2019-09-26 WO claimed
US-20190292473-A1 COMPOSITION AND METHOD FOR PREVENTING OR REDUCING LOW SPEED PRE-IGNITION IN SPARK-IGNITED INTERNAL COMBUSTION ENGINES CHEVRON ORONITE COMPANY LLC 2019-09-26 US claimed
US-20190248721-A1 PROCESSES FOR PREPARING CALIXARENES SI GROUP, INC. 2019-08-15 US claimed
WO-2019157357-A1 PROCESSES FOR PREPARING CALIXARENES SI GROUP, INC. (US) 2019-08-15 WO claimed
US-10336863-B2 Curable composition having a special catalyst/softner system HENKEL AG & CO. KGAA (DE) 2019-07-02 US claimed
US-20180237635-A1 CURABLE COATING COMPOSITIONS OF SILANE FUNCTIONAL POLYMERS KING INDUSTRIES 2018-08-23 US claimed
US-9976028-B2 Curable coating compositions of silane functional polymers KING INDUSTRIES (US) 2018-05-22 US claimed
US-20160244606-A1 CURABLE COATING COMPOSITIONS OF SILANE FUNCTIONAL POLYMERS KING INDUSTRIES 2016-08-25 US claimed
US-8013080-B2 Curable composition KANEKA CORPORATION (JP) 2011-09-06 US claimed
EP-4692247-A1 CURABLE COMPOSITION KANEKA CORPORATION (JP) 2026-02-11 EP disclosed
EP-1930376-A1 CURABLE COMPOSITION Kaneka Corporation (JP) 2008-06-11 EP disclosed
US-4524104-A ACRYLIC COPOLYMER AND BLOCKED ISOCYANATE SANYO CHEMICAL INDUSTRIES, LTD. (JP) 1985-06-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210047253-A1 PROCESSES FOR PREPARING CALIXARENES CALU, CALD1, CALR INMT 3966/4885POLB 1641/4885USP2 3712/4885
US-20190248721-A1 PROCESSES FOR PREPARING CALIXARENES CALU, CALD1, CALR INMT 3966/4885POLB 1641/4885USP2 3712/4885
US-11225450-B2 Processes for preparing calixarenes CALU, CALD1, CALR INMT 3966/4885POLB 1641/4885USP2 3712/4885
US-10781154-B2 Processes for preparing calixarenes CALU, CALD1, CALR INMT 3966/4885POLB 1641/4885USP2 3712/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.