SCHEMBL580394

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30507528	0.91	HSP90AA1 (0.53)	NCOA1NCOA3AURKAHSP90AA1PRKACA
	SCHEMBL28501185	0.91	HSP90AA1 (0.53)	NCOA1NCOA3AURKAHSP90AA1PRKACA
	SCHEMBL4726065	0.86	NCOA1 (0.51)	NCOA1NCOA3FEN1ALOX5APMEN1
	SCHEMBL580833	0.83	CLK1 (0.49)	AURKAHSP90AA1PRKACAADORA2AFEN1
	SCHEMBL974439	0.82	IKBKB (0.48)	NCOA1NCOA3AURKAIKBKB
	SCHEMBL503945	0.81	AURKA (0.51)	AURKAHSP90AA1PRKACAADORA2AFEN1
	SCHEMBL30507329	0.78	HSP90AA1 (0.60)	AURKAHSP90AA1PRKACAADORA2ADYRK1A
	SCHEMBL3362587	0.78	HSP90AA1 (0.60)	AURKAHSP90AA1PRKACAADORA2ADYRK1A
	SCHEMBL29992912	0.77	NCOA1 (0.78)	NCOA1NCOA3MEN1APAF1KMT2A
	SCHEMBL1143083	0.77	NCOA1 (0.78)	NCOA1NCOA3MEN1APAF1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.