Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | TYK2 | P29597 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.45 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.45 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.45 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7291906 | 0.82 | ALDH1A1 (0.61) | MAPTL3MBTL1TYK2MEN1KMT2A | |
| SCHEMBL5803985 | 0.80 | MAPT (0.53) | MAPTL3MBTL1TYK2MEN1KMT2A | |
| SCHEMBL7704551 | 0.80 | MAPT (0.56) | MAPTL3MBTL1TYK2KDM4EALDH1A1 | |
| SCHEMBL6327886 | 0.80 | MAPT (0.49) | MAPTL3MBTL1TYK2MEN1KMT2A | |
| SCHEMBL10681437 | 0.78 | MEN1 (0.49) | MAPTL3MBTL1TYK2MEN1KMT2A | |
| SCHEMBL11437140 | 0.78 | MEN1 (0.55) | MAPTL3MBTL1TYK2MEN1KMT2A | |
| Bromide SCHEMBL5470923 | 0.77 | MEN1 (0.47) | MAPTL3MBTL1TYK2MEN1KMT2A | |
| SCHEMBL3419678 | 0.76 | NPSR1 (0.59) | MAPTTYK2MEN1KMT2ALMNA | |
| SCHEMBL5805446 | 0.76 | KMT2A (0.53) | L3MBTL1MEN1KMT2ALMNAKDM4E | |
| SCHEMBL5803890 | 0.76 | KMT2A (0.62) | MAPTL3MBTL1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006093518-A2 | THIENYL COMPOUNDS FOR TREATING VIRUS-RELATED CONDITIONS | APATH, LLC (US) | 2006-09-08 | — | — | WO | disclosed |