Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.74 |
| ▸ | MAPT | P10636 | 4/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | TP53 | P04637 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5805462 | 0.98 | KDM4E (0.71) | KDM4EMAPTNPSR1RECQLALDH1A1 | |
| SCHEMBL13407754 | 0.89 | KDM4E (0.70) | KDM4EMAPTNPSR1RECQLALDH1A1 | |
| SCHEMBL15722389 | 0.84 | KDM4E (0.73) | KDM4EMAPTNPSR1RECQLALDH1A1 | |
| SCHEMBL13407753 | 0.81 | MAPT (0.78) | KDM4EMAPTNPSR1RECQLALDH1A1 | |
| SCHEMBL15506196 | 0.81 | KDM4E (0.68) | KDM4EMAPTNPSR1RECQLALDH1A1 | |
| SCHEMBL13407750 | 0.79 | MAPT (0.75) | KDM4EMAPTNPSR1RECQLALDH1A1 | |
| SCHEMBL20228785 | 0.79 | ALDH1A1 (0.68) | KDM4EMAPTNPSR1RECQLALDH1A1 | |
| SCHEMBL12281814 | 0.78 | ALDH1A1 (0.71) | KDM4EMAPTNPSR1RECQLALDH1A1 | |
| SCHEMBL21528235 | 0.78 | KDM4E (0.64) | KDM4EMAPTNPSR1RECQLALDH1A1 | |
| SCHEMBL19079839 | 0.77 | KDM4E (0.73) | KDM4EMAPTNPSR1RECQLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006093518-A2 | THIENYL COMPOUNDS FOR TREATING VIRUS-RELATED CONDITIONS | APATH, LLC (US) | 2006-09-08 | — | — | WO | disclosed |