Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 4/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.47 |
| ▸ | HTR3B | O95264 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | HTR3A | P46098 | 1/20 | 0.47 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.47 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22657655 | 0.79 | USP2 (0.52) | USP2CYP2D6LMNAHTR3EHTR3B | |
| SCHEMBL1709269 | 0.76 | USP2 (0.74) | USP2CYP2D6LMNAHTR3EHTR3B | |
| SCHEMBL21957634 | 0.75 | HDAC4 (0.54) | USP2CYP2D6LMNAHTR3EHTR3B | |
| SCHEMBL5365908 | 0.75 | USP2 (0.47) | USP2CYP2D6LMNAHTR3EHTR3B | |
| SCHEMBL22657483 | 0.75 | USP2 (0.47) | USP2CYP2D6LMNAHTR3EHTR3B | |
| SCHEMBL28705721 | 0.75 | MAOB (0.51) | USP2CYP2D6LMNAHTR3EHTR3B | |
| SCHEMBL4433783 | 0.75 | USP2 (0.54) | USP2CYP2D6LMNACYP2C9CYP3A4 | |
| SCHEMBL20491460 | 0.74 | NPY1R (0.48) | USP2CYP2D6LMNASIGMAR1CYP3A4 | |
| SCHEMBL13673998 | 0.74 | USP2 (0.55) | USP2CYP2D6LMNAHTR3EHTR3B | |
| SCHEMBL1107775 | 0.74 | USP2 (0.55) | USP2CYP2D6LMNAHTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1699761-A1 | CB1 MODULATOR COMPOUNDS | ELI LILLY AND COMPANY (US) | 2006-09-13 | — | — | EP | disclosed |
| WO-2005066126-A1 | CB1 MODULATOR COMPOUNDS | ELI LILLY AND COMPANY (US) | 2005-07-21 | — | — | WO | disclosed |