Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 10/20 | 0.66 |
| ▸ | MAPT | P10636 | 4/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | HTT | P42858 | 2/20 | 0.66 |
| ▸ | HPGD | P15428 | 2/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.66 |
| ▸ | RECQL | P46063 | 1/20 | 0.66 |
| ▸ | BLM | P54132 | 1/20 | 0.66 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.66 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.66 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.48 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5804241 | 0.91 | FTO (0.61) | FTOMAPTMEN1KMT2AHTT | |
| SCHEMBL5802852 | 0.85 | CYP3A4 (0.63) | FTOMAPTMEN1KMT2AHTT | |
| Fluorescein SCHEMBL27917033 | 0.83 | FTO (0.67) | FTOMAPTMEN1KMT2AHTT | |
| SCHEMBL3708020 | 0.83 | FTO (0.66) | FTOMAPTMEN1KMT2AHTT | |
| Fluorescein SCHEMBL7740743 | 0.83 | FTO (0.82) | FTOMAPTMEN1KMT2AHTT | |
| SCHEMBL30917275 | 0.82 | FTO (0.64) | FTOMAPTMEN1KMT2AHTT | |
| SCHEMBL3707886 | 0.82 | FTO (0.64) | FTOMAPTMEN1KMT2AHTT | |
| Fluorescein SCHEMBL30272223 | 0.81 | FTO (1.00) | FTOMAPTMEN1KMT2AHTT | |
| Fluorescein SCHEMBL29371199 | 0.81 | FTO (1.00) | FTOMAPTMEN1KMT2AHTT | |
| Fluorescein SCHEMBL29388667 | 0.81 | FTO (1.00) | FTOMAPTMEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006100417-A1 | ENZYME DETECTION METHOD AND REAGENT | GE HEALTHCARE UK LIMITED (GB) | 2006-09-28 | — | — | WO | disclosed |