Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.69 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.65 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.65 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.62 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 6/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26546756 | 0.89 | KDR (0.76) | KDRKCNJ5KCNJ3PDK1TRPV1 | |
| SCHEMBL4443052 | 0.86 | KDR (0.71) | KDRKCNJ5KCNJ3PDK1TRPV1 | |
| SCHEMBL13004812 | 0.86 | KDR (0.71) | KDRKCNJ5KCNJ3PDK1TRPV1 | |
| SCHEMBL28884494 | 0.85 | KDR (0.69) | KDRKCNJ5KCNJ3PDK1TRPV1 | |
| SCHEMBL14422910 | 0.85 | KDR (0.69) | KDRKCNJ5KCNJ3PDK1TRPV1 | |
| SCHEMBL5804246 | 0.85 | KDR (0.69) | KDRKCNJ5KCNJ3PDK1TRPV1 | |
| SCHEMBL2600217 | 0.85 | KDR (0.69) | KDRKCNJ5KCNJ3PDK1LMNA | |
| SCHEMBL29476070 | 0.84 | KDR (0.68) | KDRKCNJ5KCNJ3PDK1LMNA | |
| SCHEMBL28520609 | 0.84 | KDR (0.68) | KDRKCNJ5KCNJ3PDK1TRPV1 | |
| SCHEMBL2350751 | 0.84 | KDR (0.68) | KDRKCNJ5KCNJ3PDK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006093518-A2 | THIENYL COMPOUNDS FOR TREATING VIRUS-RELATED CONDITIONS | APATH, LLC (US) | 2006-09-08 | — | — | WO | disclosed |