Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TGM2 | P21980 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1753925 | 0.85 | GAA (0.70) | GAAALDH1A1HDAC3HDAC1HDAC2 | |
| SCHEMBL5806463 | 0.84 | HDAC3 (0.62) | GAAALDH1A1HDAC3HDAC1HDAC2 | |
| SCHEMBL9843748 | 0.81 | GAA (0.66) | GAAALDH1A1HDAC3HDAC1HDAC2 | |
| SCHEMBL6794740 | 0.81 | GAA (0.66) | GAAALDH1A1HDAC3HDAC1HDAC2 | |
| SCHEMBL1193345 | 0.79 | NPC1 (0.63) | GAAALDH1A1HDAC3HDAC1HDAC2 | |
| SCHEMBL5804322 | 0.79 | SMN1; SMN2 (0.59) | GAAALDH1A1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL105772 | 0.79 | GAA (0.63) | GAAALDH1A1HDAC3HDAC1HDAC2 | |
| SCHEMBL1525924 | 0.79 | GAA (0.63) | GAAALDH1A1HDAC3HDAC1HDAC2 | |
| SCHEMBL5804257 | 0.79 | GAA (0.63) | GAAALDH1A1HDAC3HDAC1HDAC2 | |
| SCHEMBL5718053 | 0.79 | GAA (0.63) | GAAALDH1A1HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006093518-A2 | THIENYL COMPOUNDS FOR TREATING VIRUS-RELATED CONDITIONS | APATH, LLC (US) | 2006-09-08 | — | — | WO | disclosed |