Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.63 |
| ▸ | MITF | O75030 | 2/20 | 0.63 |
| ▸ | RAB9A | P51151 | 2/20 | 0.63 |
| ▸ | GAA | P10253 | 2/20 | 0.63 |
| ▸ | XBP1 | P17861 | 1/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9081388 | 0.89 | NPC1 (0.76) | NPC1MITFRAB9AXBP1NPSR1 | |
| SCHEMBL10919754 | 0.88 | PRMT1 (0.84) | NPC1MITFRAB9AGAAXBP1 | |
| SCHEMBL11739018 | 0.86 | GAA (0.58) | NPC1MITFRAB9AGAAXBP1 | |
| SCHEMBL1753925 | 0.85 | GAA (0.70) | GAAALDH1A1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL3317660 | 0.84 | HDAC3 (0.62) | RAB9AGAAALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL15489874 | 0.82 | GAA (0.61) | NPC1RAB9AGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL16922181 | 0.81 | NPC1 (0.66) | NPC1MITFRAB9AGAAXBP1 | |
| SCHEMBL6794740 | 0.81 | GAA (0.66) | GAAALDH1A1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL2635734 | 0.81 | NPC1 (0.66) | NPC1MITFRAB9AGAAXBP1 | |
| SCHEMBL9843748 | 0.81 | GAA (0.66) | NPC1RAB9AGAAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 275 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220274926-A1 | IMMUNOREGULATORY AGENTS | FLEXUS BIOSCIENCES INC (US) | 2022-09-01 | — | — | US | claimed |
| CN-113234090-B | Compound for targeted ubiquitination degradation of FoxM1 or pharmaceutically acceptable salt thereof, preparation method and application | 中国药科大学 | 2022-07-29 | — | — | CN | claimed |
| CN-113234090-A | Compound for targeted ubiquitination degradation of FoxM1 or pharmaceutically acceptable salt thereof, preparation method and application | 中国药科大学 | 2021-08-10 | — | — | CN | claimed |
| CN-107400088-B | 1, 3-disubstituted pyrazole derivatives, and preparation method and application thereof | 山东大学 | 2020-04-28 | — | — | CN | claimed |
| CN-102796003-B | Preparation method of 2-fluoro-4,5-dichloronitrobenzene | UNIV CHANGZHOU | 2014-05-28 | — | — | CN | claimed |
| CN-102796003-A | Preparation method of 2-fluoro-4,5-dichloronitrobenzene | UNIV CHANGZHOU | 2012-11-28 | — | — | CN | claimed |
| CN-120058445-A | Method for generating aryl phenol compound by hydroxylation of uranium photocatalytic aryl fluorine compound and application of method | 华东师范大学 | 2025-05-30 | — | — | CN | disclosed |
| CN-118496218-A | Carbazole-oxadiazole alpha-glucosidase and alpha-amylase double-target inhibitor and preparation method and application thereof | 贵州医科大学 | 2024-08-16 | — | — | CN | disclosed |
| CN-118146172-A | Preparation method of 7-fluoro-6-amino-2H-1, 4-benzoxazine-3 (4H) -one | 帕潘纳(北京)科技有限公司 | 2024-06-07 | — | — | CN | disclosed |
| US-11932601-B2 | Immunoregulatory agents | FLEXUS BIOSCIENCES, INC. (US) | 2024-03-19 | — | — | US | disclosed |
| US-20240018135-A1 | COMPOUND HAVING INHIBITORY ACTIVITY AGAINST O-GLUSACASE AND USE THEREOF | MEDIFRON DBT INC. (KR) | 2024-01-18 | — | — | US | disclosed |
| US-20240018135-A1 | COMPOUND HAVING INHIBITORY ACTIVITY AGAINST O-GLUSACASE AND USE THEREOF | MEDIFRON DBT INC. (KR) | 2024-01-18 | — | — | US | disclosed |
| US-20240018135-A1 | COMPOUND HAVING INHIBITORY ACTIVITY AGAINST O-GLUSACASE AND USE THEREOF | MEDIFRON DBT INC. (KR) | 2024-01-18 | — | — | US | disclosed |
| WO-1997040038-A1 | PIPERIDINES AND PYRROLIDINES | MERCK PATENT GMBH (DE) | 1997-10-30 | — | — | WO | disclosed |
| US-4567264-A | ADRENERGIC BLOCKING AGENTS | SYNTEX (U.S.A.) INC. (US) | 1986-01-28 | — | — | US | disclosed |
| US-4558129-A | Benzodioxanyl-hydroxyethylene-piperazinyl acetanilides which effect calcium entry and β-blockade | SYNTEX (U.S.A.) INC. (US) | 1985-12-10 | — | — | US | disclosed |
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |
| EP-0126449-A1 | Cardioselective aryloxy- and arylthio-hydroxypropyl piperazinyl acetanilides wich affect calcium entry | SYNTEX (U.S.A.) INC. (US) | 1984-11-28 | — | — | EP | disclosed |
| US-4017631-A | MICROBIOCIDES | JANSSEN PHARMACEUTICA N.V. (BE) | 1977-04-12 | — | — | US | disclosed |
| US-3991202-A | ANTIMICROBIALS | JANSSEN PHARMACEUTICA N.V. (BE) | 1976-11-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11932601-B2 | Immunoregulatory agents | IDO1, IDO2, INMT | NPC1 3281/4885MITF 2933/4885RAB9A 3650/4885 |
| US-20220274926-A1 | IMMUNOREGULATORY AGENTS | IDO1, IDO2, INMT | NPC1 3281/4885MITF 2933/4885RAB9A 3650/4885 |
| US-20240018135-A1 | COMPOUND HAVING INHIBITORY ACTIVITY AGAINST O-GLUSACASE AND USE THEREOF | OGA, OGT, ENGASE | NPC1 3307/4885MITF 2149/4885RAB9A 2825/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.