Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2N | P61088 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5804258 | 0.86 | TSHR (0.47) | UBE2NGAAHPGDSMN1; SMN2CYP2C9 | |
| SCHEMBL5807356 | 0.86 | TSHR (0.48) | UBE2NGAAHPGDSMN1; SMN2CYP2C9 | |
| SCHEMBL6555852 | 0.81 | UBE2N (0.48) | UBE2NGAAHPGDSMN1; SMN2CYP2C9 | |
| SCHEMBL6555630 | 0.79 | PPARG (0.69) | ADRA1A | |
| SCHEMBL7753447 | 0.78 | TSHR (0.48) | UBE2NGAAHPGDSMN1; SMN2CYP2C9 | |
| SCHEMBL5935593 | 0.78 | MEN1 (0.55) | GAAHPGDSMN1; SMN2CYP2C9CYP2C19 | |
| SCHEMBL5935599 | 0.77 | MEN1 (0.57) | GAAHPGDSMN1; SMN2CYP2C9CYP2C19 | |
| SCHEMBL6555846 | 0.77 | PPARA (0.60) | UBE2NGAAHPGDSMN1; SMN2CYP2C9 | |
| SCHEMBL6555781 | 0.76 | PPARG (0.54) | GAAHPGDSMN1; SMN2CYP2C9CYP2C19 | |
| SCHEMBL5935688 | 0.76 | GFER (0.49) | UBE2NGAAHPGDSMN1; SMN2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006082495-A1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | RANBAXY LABORATORIES LIMITED (IN) | 2006-08-10 | — | — | WO | disclosed |