Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | UBE2N | P61088 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | EIF4EBP1 | Q13541 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5804256 | 0.86 | UBE2N (0.52) | TSHRUBE2NMEN1KMT2AEIF4EBP1 | |
| SCHEMBL6555912 | 0.85 | PPARG (0.53) | TSHRUBE2NMEN1KMT2AEIF4EBP1 | |
| SCHEMBL5807356 | 0.83 | TSHR (0.48) | TSHRUBE2NMEN1KMT2AEIF4EBP1 | |
| SCHEMBL6555852 | 0.81 | UBE2N (0.48) | TSHRUBE2NMEN1KMT2AEIF4EBP1 | |
| SCHEMBL7753447 | 0.77 | TSHR (0.48) | TSHRUBE2NMEN1KMT2AEIF4EBP1 | |
| SCHEMBL6555630 | 0.77 | PPARG (0.69) | ADRA1A | |
| SCHEMBL5935599 | 0.77 | MEN1 (0.57) | TSHRMEN1KMT2AGFERMAPT | |
| SCHEMBL6555819 | 0.76 | PPARG (0.52) | MAPTHRH3KCNH2 | |
| SCHEMBL6555781 | 0.76 | PPARG (0.54) | TSHRMEN1KMT2AEIF4EBP1GFER | |
| SCHEMBL5935688 | 0.75 | GFER (0.49) | TSHRUBE2NMEN1KMT2AEIF4EBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006082495-A1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | RANBAXY LABORATORIES LIMITED (IN) | 2006-08-10 | — | — | WO | disclosed |