SCHEMBL5804265

SCHEMBL5804265

[N]=CC1Oc2ccccc2O1

nearest known ligand 0.32

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.32
ABCG2 Q9UNQ0 1/20 0.32
ITGB2 P05107 1/20 0.32
ICAM1 P05362 1/20 0.32
ITGAL P20701 1/20 0.32
NISCH Q9Y2I1 2/20 0.31
MAOA P21397 1/20 0.31
MAOB P27338 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7777038 0.75 CA2 (0.31) CA2
SCHEMBL7777036 0.75 CA2 (0.31) CA2
SCHEMBL5804269 0.74 NISCH (0.35) CA2ABCG2ITGB2ICAM1ITGAL
SCHEMBL7765718 0.74 CA2 (0.32) CA2ABCG2ITGB2ICAM1ITGAL
SCHEMBL5010302 0.74 CA2 (0.41) CA2ABCG2ITGB2ICAM1ITGAL
SCHEMBL7765721 0.74 HRH3 (0.34) CA2ABCG2ITGB2ICAM1ITGAL
SCHEMBL3639080 0.74 NISCH (0.35) CA2ABCG2ITGB2ICAM1ITGAL
SCHEMBL27964898 0.72 CA2 (0.39) CA2ABCG2ITGB2ICAM1ITGAL
SCHEMBL3652062 0.70 CA2 (0.31) CA2
SCHEMBL1689227 0.69 POLB (0.34) CA2NISCH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006093518-A2 THIENYL COMPOUNDS FOR TREATING VIRUS-RELATED CONDITIONS APATH, LLC (US) 2006-09-08 WO disclosed