Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.68 |
| ▸ | MAPT | P10636 | 7/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.68 |
| ▸ | POLB | P06746 | 4/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.68 |
| ▸ | HTT | P42858 | 3/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | RECQL | P46063 | 2/20 | 0.68 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.57 |
| ▸ | GAA | P10253 | 6/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | PKM | P14618 | 2/20 | 0.57 |
| ▸ | KLF5 | Q13887 | 2/20 | 0.57 |
| ▸ | MITF | O75030 | 1/20 | 0.57 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.57 |
| ▸ | TLR2 | O60603 | 1/20 | 0.55 |
| ▸ | ERN1 | O75460 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5804270 | 1.00 | NPC1 (0.68) | NPC1MAPTSMN1; SMN2KDM4EPOLB | |
| SCHEMBL19936663 | 0.81 | MAPT (0.70) | NPC1MAPTSMN1; SMN2KDM4EPOLB | |
| SCHEMBL5804271 | 0.81 | MAPT (0.69) | NPC1MAPTSMN1; SMN2KDM4EPOLB | |
| SCHEMBL9458185 | 0.78 | KDM4E (0.74) | NPC1MAPTSMN1; SMN2KDM4EPOLB | |
| SCHEMBL19519011 | 0.77 | POLB (0.86) | NPC1MAPTSMN1; SMN2KDM4EPOLB | |
| SCHEMBL13617293 | 0.76 | MAPT (0.86) | NPC1MAPTSMN1; SMN2KDM4EPOLB | |
| SCHEMBL683795 | 0.76 | MAPT (0.86) | NPC1MAPTSMN1; SMN2KDM4EPOLB | |
| SCHEMBL6822725 | 0.76 | CA12 (0.70) | NPC1MAPTSMN1; SMN2KDM4EPOLB | |
| SCHEMBL19089795 | 0.76 | CA12 (0.70) | NPC1MAPTSMN1; SMN2KDM4EPOLB | |
| SCHEMBL17550790 | 0.76 | CA12 (0.70) | NPC1MAPTSMN1; SMN2KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006093518-A2 | THIENYL COMPOUNDS FOR TREATING VIRUS-RELATED CONDITIONS | APATH, LLC (US) | 2006-09-08 | — | — | WO | disclosed |