Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.70 |
| ▸ | TLR2 | O60603 | 1/20 | 0.62 |
| ▸ | ERN1 | O75460 | 1/20 | 0.62 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.62 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 8/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6822726 | 1.00 | CA12 (0.70) | CA12TLR2ERN1TLR1TLR6 | |
| SCHEMBL17550790 | 1.00 | CA12 (0.70) | CA12TLR2ERN1TLR1TLR6 | |
| SCHEMBL19089795 | 0.85 | CA12 (0.70) | CA12TLR2ERN1TLR1TLR6 | |
| SCHEMBL2317614 | 0.84 | CA12 (0.68) | CA12TLR2ERN1TLR1TLR6 | |
| SCHEMBL20363500 | 0.84 | CA12 (0.68) | CA12TLR2ERN1TLR1TLR6 | |
| SCHEMBL3776981 | 0.84 | MAPT (0.77) | CA12TLR2ERN1TLR1TLR6 | |
| SCHEMBL2186863 | 0.83 | HPGD (0.56) | CA12TLR2ERN1TLR1TLR6 | |
| SCHEMBL2186861 | 0.83 | HPGD (0.56) | CA12TLR2ERN1TLR1TLR6 | |
| SCHEMBL2420718 | 0.82 | HPGD (0.69) | MAPTKDM4ELMNASMN1; SMN2HTT | |
| SCHEMBL2160891 | 0.82 | HPGD (0.69) | MAPTKDM4ELMNASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114262282-B | Aldoxime compound and preparation method and application thereof | 广东省科学院资源利用与稀土开发研究所 | 2024-04-19 | — | — | CN | disclosed |
| CN-114262282-A | Aldoxime compound and preparation method and application thereof | 广东省科学院资源利用与稀土开发研究所 | 2022-04-01 | — | — | CN | disclosed |
| WO-2004067518-A1 | SUBSTITUTED PYRIMIDINES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2004-08-12 | — | — | WO | disclosed |
| US-5100532-A | In liquid hydrocarbonaceous media | BETZ LABORATORIES, INC. (US) | 1992-03-31 | — | — | US | disclosed |