Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5800708 | 0.90 | TRPV1 (0.75) | TRPV1 | |
| SCHEMBL5801528 | 0.86 | EPHX2 (0.60) | TRPV1 | |
| SCHEMBL4623761 | 0.84 | TRPV1 (0.86) | TRPV1 | |
| SCHEMBL5804728 | 0.82 | TRPV1 (0.57) | TRPV1 | |
| SCHEMBL5804726 | 0.82 | TRPV1 (0.57) | TRPV1 | |
| SCHEMBL5801108 | 0.81 | TRPV1 (0.58) | TRPV1 | |
| SCHEMBL5800933 | 0.80 | EPHX2 (0.67) | — | |
| SCHEMBL5803989 | 0.79 | — | — | |
| SCHEMBL5802640 | 0.78 | — | — | |
| SCHEMBL1268701 | 0.78 | TRPV1 (1.00) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006098554-A1 | NOVEL COMPOUNDS, ISOMER THEREOF OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AS VANILLOID RECEPTOR ANTAGONIST; AND A PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | AMOREPACIFIC CORPORATION (KR) | 2006-09-21 | — | — | WO | disclosed |