Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.67 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.67 |
| ▸ | PPARG | P37231 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5801475 | 0.89 | EPHX2 (0.72) | EPHX2NR1H4PPARG | |
| SCHEMBL5803989 | 0.86 | — | — | |
| SCHEMBL5800708 | 0.85 | TRPV1 (0.75) | — | |
| SCHEMBL5801396 | 0.81 | — | — | |
| SCHEMBL21990340 | 0.81 | EPHX2 (1.00) | EPHX2NR1H4PPARG | |
| SCHEMBL5804361 | 0.80 | TRPV1 (0.64) | — | |
| SCHEMBL5801613 | 0.80 | — | — | |
| SCHEMBL5715986 | 0.78 | EPHX2 (0.59) | EPHX2NR1H4PPARG | |
| SCHEMBL5820867 | 0.78 | — | — | |
| SCHEMBL5802264 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006098554-A1 | NOVEL COMPOUNDS, ISOMER THEREOF OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AS VANILLOID RECEPTOR ANTAGONIST; AND A PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | AMOREPACIFIC CORPORATION (KR) | 2006-09-21 | — | — | WO | claimed |
| WO-2006098554-A1 | NOVEL COMPOUNDS, ISOMER THEREOF OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AS VANILLOID RECEPTOR ANTAGONIST; AND A PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | AMOREPACIFIC CORPORATION (KR) | 2006-09-21 | — | — | WO | disclosed |