Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT2 | O75908 | 1/20 | 0.64 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.64 |
| ▸ | HDAC8 | Q9BY41 | 16/20 | 0.63 |
| ▸ | HDAC6 | Q9UBN7 | 15/20 | 0.63 |
| ▸ | HDAC2 | Q92769 | 15/20 | 0.63 |
| ▸ | HDAC4 | P56524 | 14/20 | 0.63 |
| ▸ | HDAC1 | Q13547 | 14/20 | 0.63 |
| ▸ | HDAC7 | Q8WUI4 | 14/20 | 0.63 |
| ▸ | HDAC11 | Q96DB2 | 14/20 | 0.63 |
| ▸ | HDAC9 | Q9UKV0 | 14/20 | 0.63 |
| ▸ | HDAC5 | Q9UQL6 | 14/20 | 0.63 |
| ▸ | HDAC3 | O15379 | 13/20 | 0.63 |
| ▸ | HDAC10 | Q969S8 | 13/20 | 0.63 |
| ▸ | NCOR1 | O75376 | 2/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | BRD4 | O60885 | 1/20 | 0.63 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.63 |
| ▸ | EGFR | P00533 | 1/20 | 0.63 |
| ▸ | LTA4H | P09960 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28476333 | 0.98 | SOAT2 (0.67) | SOAT2SOAT1HDAC8HDAC6HDAC2 | |
| SCHEMBL12832783 | 0.98 | SOAT2 (0.67) | SOAT2SOAT1HDAC8HDAC6HDAC2 | |
| SCHEMBL11328654 | 0.95 | HDAC8 (0.60) | SOAT2SOAT1HDAC8HDAC6HDAC2 | |
| SCHEMBL2577548 | 0.88 | NAMPT (0.62) | SOAT2SOAT1HDAC8HDAC6HDAC2 | |
| SCHEMBL517309 | 0.86 | HDAC4 (0.81) | HDAC8HDAC6HDAC2HDAC4HDAC1 | |
| SCHEMBL28622501 | 0.85 | PSMB11 (0.65) | SOAT2SOAT1HDAC8HDAC6HDAC2 | |
| SCHEMBL8171773 | 0.85 | SOAT2 (0.66) | SOAT2SOAT1HDAC8HDAC6HDAC2 | |
| SCHEMBL29005915 | 0.84 | HDAC3 (0.65) | HDAC8HDAC6HDAC2HDAC4HDAC1 | |
| SCHEMBL1065393 | 0.84 | HDAC4 (0.85) | HDAC8HDAC6HDAC2HDAC4HDAC1 | |
| SCHEMBL6669511 | 0.84 | HDAC4 (0.85) | HDAC8HDAC6HDAC2HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116143844-A | Hydrophilic trimeric indenyl metal organic nickel octahedral cage and preparation method and application thereof | 江苏科技大学 | 2023-05-23 | — | — | CN | disclosed |
| WO-2006069096-A1 | SILANOL DERIVATIVES AS INHIBITORS OF HISTONE DEACETYLASE | PHARMACYCLICS, INC. (US) | 2006-06-29 | — | — | WO | disclosed |
| WO-2006069096-A1 | SILANOL DERIVATIVES AS INHIBITORS OF HISTONE DEACETYLASE | PHARMACYCLICS, INC. (US) | 2006-06-29 | — | — | WO | disclosed |