Known targets — ChEMBL curated mechanism
SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9A
The experimentally established mechanism targets of Gluconic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3708519 | 0.87 | PDE4A (0.44) | PDE4ALMNAUSP2SLCO1B1 | |
| SCHEMBL3709949 | 0.87 | PDE4A (0.44) | PDE4ALMNAUSP2SLCO1B1 | |
| Gluconic Acid SCHEMBL23069530 | 0.82 | PDE4A (0.70) | PDE4ALMNAUSP2SLCO1B1FFAR3 | |
| Gluconic Acid SCHEMBL30666301 | 0.82 | PDE4A (0.70) | PDE4ALMNAUSP2SLCO1B1FFAR3 | |
| Gluconic Acid SCHEMBL5086286 | 0.82 | PDE4A (0.70) | PDE4ALMNAUSP2SLCO1B1FFAR3 | |
| Butyric Acid SCHEMBL23069534 | 0.81 | PDE4A (0.68) | PDE4ALMNAUSP2SLCO1B1FFAR3 | |
| SCHEMBL16144865 | 0.75 | PDE4A (0.44) | PDE4ALMNAUSP2SLCO1B1 | |
| Gluconic Acid SCHEMBL9193549 | 0.74 | PDE4A (0.79) | PDE4ALMNAUSP2SLCO1B1FFAR3 | |
| Mannitol SCHEMBL18141296 | 0.74 | FFAR3 (0.59) | PDE4ALMNAUSP2SLCO1B1FFAR3 | |
| Mannitol SCHEMBL28176051 | 0.74 | FFAR3 (0.59) | PDE4ALMNAUSP2SLCO1B1FFAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006110119-A1 | ANTINEOPLASTIC PREPARATION | KUTNYAK VICTOR PAVLOVICH (UA) | 2006-10-19 | — | — | WO | disclosed |