Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3708519 | 1.00 | PDE4A (0.44) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| Gluconic Acid SCHEMBL5804547 | 0.87 | PDE4A (0.47) | PDE4ALMNAUSP2SLCO1B1 | |
| SCHEMBL4393096 | 0.84 | PDE4A (0.42) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| SCHEMBL1001815 | 0.82 | PDE4A (0.50) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| SCHEMBL4395659 | 0.80 | PDE4A (0.44) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| SCHEMBL1656749 | 0.79 | PDE4A (0.50) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| SCHEMBL8465610 | 0.78 | PDE4A (0.54) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| SCHEMBL3289378 | 0.77 | PDE4A (0.48) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| SCHEMBL6274785 | 0.77 | PDE4A (0.52) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| SCHEMBL16144865 | 0.77 | PDE4A (0.44) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120122981-A1 | Biomarkers Related to Insulin Resistance and Methods using the Same | METABOLON, INC. | 2012-05-17 | — | — | US | disclosed |