Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 15/20 | 0.37 |
| ▸ | PPARG | P37231 | 15/20 | 0.37 |
| ▸ | PPARD | Q03181 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.33 |
| ▸ | KIFC1 | Q9BW19 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1749462 | 0.93 | PPARA (0.42) | PPARAPPARGPPARDNPC1ALDH1A1 | |
| SCHEMBL1750232 | 0.93 | PPARA (0.42) | PPARAPPARGPPARDNPC1ALDH1A1 | |
| SCHEMBL1750943 | 0.92 | PPARA (0.42) | PPARAPPARGPPARDNPC1ALDH1A1 | |
| SCHEMBL1749698 | 0.86 | NPC1 (0.38) | PPARAPPARGNPC1ALDH1A1RAB9A | |
| SCHEMBL1750052 | 0.85 | PPARA (0.44) | PPARAPPARGPPARD | |
| SCHEMBL1750054 | 0.85 | PPARA (0.44) | PPARAPPARGPPARD | |
| SCHEMBL1749615 | 0.85 | NPC1 (0.37) | PPARAPPARGNPC1ALDH1A1RAB9A | |
| SCHEMBL2221312 | 0.85 | PTGS2 (0.37) | NPC1ALDH1A1RAB9ALTB4R2KIFC1 | |
| SCHEMBL1750188 | 0.84 | PPARG (0.45) | PPARAPPARGPPARD | |
| SCHEMBL1750190 | 0.84 | PPARG (0.45) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1638964-A1 | NOVEL COMPOUNDS THAT MODULATE PPAR-GAMMA TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | Galderma Research & Development, S.N.C. (FR) | 2006-03-29 | — | — | EP | disclosed |
| WO-2004113331-A1 | NOVEL COMPOUNDS THAT MODULATE PPARϜ TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-12-29 | — | — | WO | disclosed |