Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | HTR7 | P34969 | 1/20 | 0.52 |
| ▸ | RAD52 | P43351 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.47 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5169313 | 0.86 | PTPN1 (0.55) | PTPN1NPC1RAB9AHTR7RAD52 | |
| SCHEMBL5635153 | 0.82 | PTPN1 (0.52) | PTPN1NPC1RAB9AHTR7RAD52 | |
| SCHEMBL31274029 | 0.82 | GSK3B (0.55) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL4582312 | 0.82 | HSD17B3 (0.53) | PTPN1NPC1RAB9AADRB2ADRB1 | |
| SCHEMBL4686815 | 0.81 | MEN1 (0.54) | PTPN1NPC1RAB9AHTR7RAD52 | |
| SCHEMBL22473526 | 0.80 | PTPN1 (0.46) | PTPN1NPC1RAB9AHTR7RAD52 | |
| SCHEMBL21834949 | 0.80 | USP5 (0.59) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL3323233 | 0.80 | KMT2A (0.52) | NPC1RAB9AKMT2ADPP4POLB | |
| SCHEMBL9806762 | 0.80 | ADRB2 (0.47) | NPC1RAB9AMEN1KMT2AADRB2 | |
| SCHEMBL9756778 | 0.79 | PTPN1 (0.48) | PTPN1NPC1RAB9AHTR7RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006089038-A2 | INSECTICIDAL TETRAHYDROINDENOPYRIDINE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2006-08-24 | — | — | WO | disclosed |