Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | TSHR | P16473 | 4/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 3/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | BACE1 | P56817 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5805038 | 0.98 | POLB (0.64) | NPSR1ALDH1A1SMN1; SMN2MAPTTSHR | |
| SCHEMBL3911841 | 0.91 | TP53 (0.68) | NPSR1ALDH1A1SMN1; SMN2MAPTTSHR | |
| SCHEMBL1101912 | 0.84 | ALDH1A1 (0.66) | NPSR1ALDH1A1SMN1; SMN2MAPTTSHR | |
| SCHEMBL19079782 | 0.84 | TSHR (0.73) | NPSR1ALDH1A1SMN1; SMN2MAPTTSHR | |
| SCHEMBL1102247 | 0.82 | POLB (0.66) | NPSR1ALDH1A1SMN1; SMN2MAPTTSHR | |
| SCHEMBL3914163 | 0.81 | ALDH1A1 (0.77) | NPSR1ALDH1A1SMN1; SMN2MAPTTSHR | |
| SCHEMBL19079821 | 0.79 | TSHR (0.67) | NPSR1ALDH1A1SMN1; SMN2MAPTTSHR | |
| SCHEMBL19079669 | 0.79 | SMN1; SMN2 (0.76) | NPSR1ALDH1A1SMN1; SMN2MAPTTSHR | |
| SCHEMBL19079672 | 0.78 | TSHR (1.00) | NPSR1ALDH1A1SMN1; SMN2MAPTTSHR | |
| SCHEMBL19090776 | 0.78 | RXFP1 (0.65) | NPSR1ALDH1A1SMN1; SMN2MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006093518-A2 | THIENYL COMPOUNDS FOR TREATING VIRUS-RELATED CONDITIONS | APATH, LLC (US) | 2006-09-08 | — | — | WO | disclosed |