Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.47 |
| ▸ | ANTXR2 | P58335 | 1/20 | 0.40 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | AXL | P30530 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | NEK2 | P51955 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.40 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
| ▸ | NEK6 | Q9HC98 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10135392 | 0.90 | KDM4E (0.46) | KDM4EMEN1MAPTKMT2APTGS1 | |
| SCHEMBL10181482 | 0.86 | KMT2A (0.42) | KDM4EMEN1MAPTKMT2APTGS1 | |
| SCHEMBL10182055 | 0.84 | MEN1 (0.46) | KDM4EMEN1MAPTKMT2APTGS1 | |
| SCHEMBL10181447 | 0.81 | PTGS1 (0.65) | KDM4EMEN1MAPTKMT2APTGS1 | |
| SCHEMBL581710 | 0.80 | KDM4E (0.44) | KDM4EMEN1MAPTKMT2APTGS1 | |
| SCHEMBL10181747 | 0.80 | MGAM (0.57) | KDM4EMEN1MAPTKMT2APTGS1 | |
| SCHEMBL10182556 | 0.79 | NUAK1 (0.56) | KDM4EMEN1MAPTKMT2APTGS1 | |
| SCHEMBL10166851 | 0.78 | CHEK1 (0.39) | KDM4EMEN1MAPTKMT2APTGS1 | |
| SCHEMBL580570 | 0.77 | PTGS1 (0.51) | KDM4EMEN1MAPTKMT2APTGS1 | |
| SCHEMBL10135390 | 0.76 | KDM4E (0.46) | KDM4EMEN1MAPTKMT2APTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121141-B1 | COUMESTAN-LIKE ANTIOXIDANTS AND UV ABSORBANTS | BASF SE (DE) | 2012-02-15 | — | — | EP | claimed |
| US-20100330009-A1 | COUMESTAN-LIKE ANTIOXIDANTS AND UV ABSORBANTS | CIBA CORPORATION (US) | 2010-12-30 | — | — | US | claimed |
| EP-2121141-A1 | COUMESTAN-LIKE ANTIOXIDANTS AND UV ABSORBANTS | BASF SE (DE) | 2009-11-25 | — | — | EP | claimed |
| WO-2008110465-A1 | COUMESTAN-LIKE ANTIOXIDANTS AND UV ABSORBANTS | BASF SE (CH) | 2008-09-18 | — | — | WO | claimed |
| EP-2464739-B1 | METHODS IN CELL CULTURES, AND RELATED INVENTIONS, EMPLOYING CERTAIN ADDITIVES | BASF SE (DE) | 2016-01-13 | — | — | EP | disclosed |
| US-8859235-B2 | Methods in cell cultures, and related inventions, employing certain additives | BASF SE (DE) | 2014-10-14 | — | — | US | disclosed |
| US-8383088-B2 | Coumestan-like antioxidants and UV absorbants | BASF SE (DE) | 2013-02-26 | — | — | US | disclosed |
| EP-2121141-B1 | COUMESTAN-LIKE ANTIOXIDANTS AND UV ABSORBANTS | BASF SE (DE) | 2012-02-15 | — | — | EP | disclosed |
| EP-2121141-B1 | COUMESTAN-LIKE ANTIOXIDANTS AND UV ABSORBANTS | BASF SE (DE) | 2012-02-15 | — | — | EP | disclosed |
| WO-2011018472-A2 | METHODS IN CELL CULTURES, AND RELATED INVENTIONS, EMPLOYING CERTAIN ADDITIVES | BASF SE (DE) | 2011-02-17 | — | — | WO | disclosed |
| US-20100330009-A1 | COUMESTAN-LIKE ANTIOXIDANTS AND UV ABSORBANTS | CIBA CORPORATION (US) | 2010-12-30 | — | — | US | disclosed |
| EP-2121141-A1 | COUMESTAN-LIKE ANTIOXIDANTS AND UV ABSORBANTS | BASF SE (DE) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008110465-A1 | COUMESTAN-LIKE ANTIOXIDANTS AND UV ABSORBANTS | BASF SE (CH) | 2008-09-18 | — | — | WO | disclosed |
| WO-2008110465-A1 | COUMESTAN-LIKE ANTIOXIDANTS AND UV ABSORBANTS | BASF SE (CH) | 2008-09-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100330009-A1 | COUMESTAN-LIKE ANTIOXIDANTS AND UV ABSORBANTS | TYR, NQO1, SIRT3 | KDM4E 1307/4885MEN1 3538/4885MAPT 1771/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.