Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | RECQL | P46063 | 5/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.41 |
| ▸ | BLM | P54132 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | PKM | P14618 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 3/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
| ▸ | EED | O75530 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10135390 | 0.90 | KDM4E (0.46) | MEN1KMT2AKDM4EMAPTRECQL | |
| SCHEMBL580508 | 0.84 | KDM4E (0.47) | MEN1KMT2AKDM4EMAPTRECQL | |
| SCHEMBL10181450 | 0.81 | PTGS1 (0.51) | MEN1KMT2AKDM4EMAPTRECQL | |
| SCHEMBL580867 | 0.81 | MEN1 (0.61) | MEN1KMT2AKDM4EMAPTRECQL | |
| SCHEMBL581188 | 0.80 | KDM4E (0.59) | MEN1KMT2AKDM4EMAPTRECQL | |
| SCHEMBL10181404 | 0.79 | KDM4E (0.42) | MEN1KMT2AKDM4EMAPTRECQL | |
| SCHEMBL10135392 | 0.78 | KDM4E (0.46) | MEN1KMT2AKDM4EMAPTCYP3A4 | |
| SCHEMBL580976 | 0.78 | KDM4E (0.44) | MEN1KMT2AKDM4EMAPTRECQL | |
| SCHEMBL10181482 | 0.74 | KMT2A (0.42) | MEN1KMT2AKDM4EMAPTRECQL | |
| SCHEMBL16167899 | 0.73 | PGAM1 (0.45) | MEN1KMT2AKDM4EMAPTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2464739-B1 | METHODS IN CELL CULTURES, AND RELATED INVENTIONS, EMPLOYING CERTAIN ADDITIVES | BASF SE (DE) | 2016-01-13 | — | — | EP | disclosed |
| US-8859235-B2 | Methods in cell cultures, and related inventions, employing certain additives | BASF SE (DE) | 2014-10-14 | — | — | US | disclosed |
| EP-2121141-B1 | COUMESTAN-LIKE ANTIOXIDANTS AND UV ABSORBANTS | BASF SE (DE) | 2012-02-15 | — | — | EP | disclosed |
| WO-2011018472-A2 | METHODS IN CELL CULTURES, AND RELATED INVENTIONS, EMPLOYING CERTAIN ADDITIVES | BASF SE (DE) | 2011-02-17 | — | — | WO | disclosed |
| WO-2008110465-A1 | COUMESTAN-LIKE ANTIOXIDANTS AND UV ABSORBANTS | BASF SE (CH) | 2008-09-18 | — | — | WO | disclosed |