Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 3/20 | 0.45 |
| ▸ | CA9 | Q16790 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | TERT | O14746 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL84809 | 0.82 | ALDH1A1 (0.55) | MAPTALDH1A1KDM4ECYP2D6KMT2A | |
| SCHEMBL84807 | 0.80 | ALDH1A1 (0.58) | MAPTALDH1A1KDM4ECYP2D6KMT2A | |
| SCHEMBL13462681 | 0.79 | ALDH1A1 (0.61) | MAPTALDH1A1KDM4ECYP2D6KMT2A | |
| SCHEMBL84386 | 0.78 | CA12 (0.55) | MAPTALDH1A1KDM4ECYP2D6KMT2A | |
| SCHEMBL13661591 | 0.78 | MAPT (0.70) | MAPTALDH1A1KDM4ECYP2D6KMT2A | |
| SCHEMBL20900504 | 0.78 | KDM4E (0.57) | MAPTALDH1A1KDM4ECYP2D6KMT2A | |
| SCHEMBL13661579 | 0.78 | ALDH1A1 (0.64) | MAPTALDH1A1KDM4ECYP2D6KMT2A | |
| Hydrochloric Acid SCHEMBL23722070 | 0.76 | CA12 (0.53) | ALDH1A1KDM4ECYP2D6KMT2AMEN1 | |
| SCHEMBL84849 | 0.76 | ALDH1A1 (0.57) | MAPTALDH1A1KDM4ECYP2D6KMT2A | |
| SCHEMBL21998915 | 0.76 | KDM4E (0.59) | MAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006077387-A2 | NOVEL BENZAMIDE DERIVATIVES | ASTRAZENECA AB (SE) | 2006-07-27 | — | — | WO | disclosed |