Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 12/20 | 0.60 |
| ▸ | DRD2 | P14416 | 6/20 | 0.50 |
| ▸ | HTR1A | P08908 | 4/20 | 0.50 |
| ▸ | HTR2A | P28223 | 4/20 | 0.50 |
| ▸ | DRD3 | P35462 | 4/20 | 0.50 |
| ▸ | HTR6 | P50406 | 3/20 | 0.50 |
| ▸ | DRD4 | P21917 | 3/20 | 0.50 |
| ▸ | HTR7 | P34969 | 2/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.49 |
| ▸ | DRD1 | P21728 | 2/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.49 |
| ▸ | HRH1 | P35367 | 2/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5805853 | 0.99 | KDM1A (0.59) | KDM1ADRD2HTR1AHTR2ADRD3 | |
| SCHEMBL5805658 | 0.93 | KDM1A (0.67) | KDM1ADRD2HTR1AHTR2ADRD3 | |
| Hydrochloric Acid SCHEMBL5807965 | 0.92 | KDM1A (0.65) | KDM1ADRD2HTR1AHTR2ADRD3 | |
| SCHEMBL5816627 | 0.89 | KDM1A (0.48) | KDM1ADRD2HTR1AHTR2ADRD3 | |
| Hydrochloric Acid SCHEMBL5809408 | 0.83 | KDM1A (0.62) | KDM1ADRD2HTR1AHTR2ADRD3 | |
| SCHEMBL5821612 | 0.82 | KDM1A (0.53) | KDM1ADRD2HTR1AHTR2ADRD3 | |
| Hydrochloric Acid SCHEMBL5821923 | 0.81 | KDM1A (0.52) | KDM1ADRD2HTR1AHTR2ADRD3 | |
| SCHEMBL5804945 | 0.81 | KDM1A (0.67) | KDM1ADRD2HTR1ADRD3HTR7 | |
| Hydrochloric Acid SCHEMBL5808276 | 0.80 | KDM1A (0.66) | KDM1ADRD2HTR1ADRD3HTR7 | |
| SCHEMBL5809272 | 0.78 | KDM1A (0.63) | KDM1ADRD2HTR1AHTR2ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006117760-A1 | ADRENERGIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-11-09 | — | — | WO | claimed |
| WO-2006117760-A1 | ADRENERGIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-11-09 | — | — | WO | disclosed |