Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 9/20 | 0.48 |
| ▸ | DRD2 | P14416 | 5/20 | 0.46 |
| ▸ | HTR1A | P08908 | 3/20 | 0.46 |
| ▸ | HTR7 | P34969 | 3/20 | 0.46 |
| ▸ | HTR6 | P50406 | 3/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 3/20 | 0.43 |
| ▸ | DRD3 | P35462 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5821612 | 0.94 | KDM1A (0.53) | KDM1ADRD2HTR1AHTR7HTR6 | |
| Hydrochloric Acid SCHEMBL5821923 | 0.93 | KDM1A (0.52) | KDM1ADRD2HTR1AHTR7HTR6 | |
| SCHEMBL5805249 | 0.89 | KDM1A (0.60) | KDM1ADRD2HTR1AHTR7HTR6 | |
| Hydrochloric Acid SCHEMBL5805853 | 0.88 | KDM1A (0.59) | KDM1ADRD2HTR1AHTR7HTR6 | |
| SCHEMBL5816138 | 0.87 | DRD2 (0.52) | KDM1ADRD2HTR1AHTR7HTR6 | |
| Hydrochloric Acid SCHEMBL5819949 | 0.86 | DRD2 (0.51) | KDM1ADRD2HTR1AHTR7HTR2A | |
| SCHEMBL5816386 | 0.84 | DRD2 (0.56) | KDM1ADRD2HTR1AHTR7HTR2A | |
| SCHEMBL5805658 | 0.83 | KDM1A (0.67) | KDM1ADRD2HTR1AHTR7HTR6 | |
| SCHEMBL5817869 | 0.82 | ADRA1A (0.51) | KDM1AHTR1ADRD4 | |
| Hydrochloric Acid SCHEMBL5807965 | 0.82 | KDM1A (0.65) | KDM1ADRD2HTR1AHTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006117760-A1 | ADRENERGIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-11-09 | — | — | WO | disclosed |