Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 1/20 | 0.48 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | ANPEP | P15144 | 2/20 | 0.45 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.45 |
| ▸ | BACE1 | P56817 | 9/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | CTSD | P07339 | 1/20 | 0.43 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4047960 | 1.00 | GRIN2B (0.48) | GRIN2BCSNK1EF2ANPEPERAP2 | |
| SCHEMBL14253003 | 1.00 | GRIN2B (0.48) | GRIN2BCSNK1EF2ANPEPERAP2 | |
| Hydrochloric Acid SCHEMBL6111346 | 0.98 | GRIN2B (0.47) | GRIN2BCSNK1EF2ANPEPERAP2 | |
| SCHEMBL4692517 | 0.94 | ANPEP (0.49) | GRIN2BCSNK1EF2ANPEPERAP2 | |
| SCHEMBL5930121 | 0.94 | ANPEP (0.52) | GRIN2BCSNK1EF2ANPEPERAP2 | |
| SCHEMBL4691199 | 0.93 | CSNK1E (0.45) | GRIN2BCSNK1EF2ANPEPERAP2 | |
| Hydrochloric Acid SCHEMBL5216767 | 0.93 | ANPEP (0.48) | GRIN2BCSNK1EF2ANPEPERAP2 | |
| SCHEMBL4693744 | 0.93 | ANPEP (0.54) | GRIN2BCSNK1EF2ANPEPERAP2 | |
| SCHEMBL4695118 | 0.93 | ANPEP (0.54) | GRIN2BCSNK1EF2ANPEPERAP2 | |
| SCHEMBL4047072 | 0.93 | ANPEP (0.54) | GRIN2BCSNK1EF2ANPEPERAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006103088-A1 | NOVEL HYDROXYETHYLAMINE AND KETONE COMPOUNDS HAVING ASP2 INHIBITORY ACTIVITY | GLAXO GROUP LIMITED (GB) | 2006-10-05 | — | — | WO | disclosed |