Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 3/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5811008 | 0.87 | DYRK1A (0.54) | DYRK1AALDH1A1LMNAHTTHIF1A | |
| Hydrochloric Acid SCHEMBL5810349 | 0.86 | DYRK1A (0.53) | DYRK1AALDH1A1LMNAHTTHIF1A | |
| SCHEMBL5808653 | 0.78 | SLC6A3 (0.43) | DYRK1AALDH1A1KDM4E | |
| SCHEMBL5807515 | 0.77 | DYRK1A (0.41) | DYRK1AALDH1A1LMNAHTTHIF1A | |
| Hydrochloric Acid SCHEMBL5805954 | 0.72 | HRH3 (0.37) | L3MBTL3L3MBTL1HRH3MBTD1OPRK1 | |
| SCHEMBL5806746 | 0.72 | PDE3A (0.47) | DYRK1A | |
| Hydrochloric Acid SCHEMBL5810956 | 0.71 | HRH3 (0.38) | KCNH2L3MBTL3L3MBTL1HRH3OPRK1 | |
| SCHEMBL5811713 | 0.70 | HRH3 (0.36) | L3MBTL3L3MBTL1HRH3OPRK1 | |
| Hydrochloric Acid SCHEMBL5808672 | 0.69 | HRH3 (0.35) | L3MBTL3L3MBTL1HRH3OPRK1 | |
| Hydrochloric Acid SCHEMBL5806874 | 0.69 | HRH3 (0.48) | ALDH1A1L3MBTL3L3MBTL1HRH3MBTD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025717-A1 | PYRROLO[2,3-c]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2006-03-09 | — | — | WO | claimed |
| WO-2006025717-A1 | PYRROLO[2,3-c]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2006-03-09 | — | — | WO | disclosed |