Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.74 |
| ▸ | RAB9A | P51151 | 4/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.74 |
| ▸ | POLB | P06746 | 2/20 | 0.72 |
| ▸ | MEN1 | O00255 | 4/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.70 |
| ▸ | NPC1 | O15118 | 3/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 1/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.70 |
| ▸ | USP2 | O75604 | 1/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.69 |
| ▸ | ATM | Q13315 | 1/20 | 0.69 |
| ▸ | GAA | P10253 | 1/20 | 0.68 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5804325 | 0.99 | ALDH1A1 (0.76) | ALDH1A1RAB9ASMN1; SMN2POLBMEN1 | |
| SCHEMBL5805290 | 0.97 | ALDH1A1 (0.70) | ALDH1A1RAB9ASMN1; SMN2POLBMEN1 | |
| SCHEMBL6248815 | 0.87 | MEN1 (0.81) | ALDH1A1RAB9ASMN1; SMN2POLBMEN1 | |
| SCHEMBL6246144 | 0.86 | MEN1 (0.83) | ALDH1A1RAB9ASMN1; SMN2POLBMEN1 | |
| SCHEMBL11369250 | 0.86 | ALDH1A1 (0.97) | ALDH1A1RAB9ASMN1; SMN2POLBMEN1 | |
| SCHEMBL5806395 | 0.86 | ALDH1A1 (0.74) | ALDH1A1RAB9ASMN1; SMN2POLBMEN1 | |
| SCHEMBL5804321 | 0.85 | ALDH1A1 (0.76) | ALDH1A1RAB9ASMN1; SMN2POLBMEN1 | |
| SCHEMBL6247335 | 0.84 | ALDH1A1 (0.71) | ALDH1A1RAB9ASMN1; SMN2POLBMEN1 | |
| SCHEMBL6246194 | 0.84 | MEN1 (0.76) | ALDH1A1RAB9ASMN1; SMN2POLBMEN1 | |
| SCHEMBL11373858 | 0.84 | MEN1 (0.97) | ALDH1A1RAB9ASMN1; SMN2POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006093518-A2 | THIENYL COMPOUNDS FOR TREATING VIRUS-RELATED CONDITIONS | APATH, LLC (US) | 2006-09-08 | — | — | WO | disclosed |