SCHEMBL5806772

SCHEMBL5806772

Cc1nc(Cn2c(C)c(C)c3ccnc(OCCc4ccc(F)cc4)c32)cs1

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
RIPK3 Q9Y572 1/20 0.39
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
RAB9A P51151 1/20 0.34
KMT2A Q03164 1/20 0.34
PDE10A Q9Y233 2/20 0.31
ELOVL1 Q9BW60 2/20 0.31
OPRK1 P41145 1/20 0.31
SREBF2 Q12772 1/20 0.30
FABP6 P51161 1/20 0.30
SCN5A Q14524 1/20 0.30
SCN9A Q15858 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5810259 0.99 RIPK3 (0.38) RIPK3CYP1A2CYP3A4CYP2D6CYP2C9
Hydrochloric Acid SCHEMBL5808677 0.84 CYP1A2 (0.40) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
Hydrochloric Acid SCHEMBL5811598 0.82 PDE1A (0.33) RIPK3FABP6
Hydrochloric Acid SCHEMBL5808743 0.81 CYP1A2 (0.38) RIPK3CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL5809727 0.81 CYP1A2 (0.41) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
Hydrochloric Acid SCHEMBL5810230 0.81 FABP4 (0.45) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
Hydrochloric Acid SCHEMBL5810709 0.81 MAPT (0.40) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
Hydrochloric Acid SCHEMBL5811503 0.80 CYP1A2 (0.40) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL5810439 0.80 PTGDR2 (0.39) RIPK3CYP1A2CYP3A4CYP2D6CYP2C9
Hydrochloric Acid SCHEMBL5808640 0.80 PDE1A (0.33) RIPK3FABP6SCN5ASCN9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006025717-A1 PYRROLO[2,3-c]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF YUHAN CORPORATION (KR) 2006-03-09 WO disclosed