SCHEMBL5807286

SCHEMBL5807286

Cc1c(C)n(CC(C)C)c2c(OCc3ccc(F)cc3)nccc12

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.49
CYP3A4 P08684 1/20 0.49
CYP2D6 P10635 1/20 0.49
CYP2C9 P11712 1/20 0.49
CYP2C19 P33261 1/20 0.49
CNR1 P21554 4/20 0.37
CNR2 P34972 4/20 0.37
KDM4E B2RXH2 3/20 0.36
ALDH1A1 P00352 2/20 0.36
TSHR P16473 2/20 0.36
HPGD P15428 1/20 0.36
HSD17B10 Q99714 1/20 0.36
APOBEC3G Q9HC16 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.34
MAPK14 Q16539 1/20 0.34
KMT2A Q03164 3/20 0.34
MPO P05164 1/20 0.34
MEN1 O00255 2/20 0.33
KDM5A P29375 2/20 0.33
KDM5B Q9UGL1 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5811245 0.99 CYP1A2 (0.48) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
Sulfuric Acid SCHEMBL5810887 0.94 CYP1A2 (0.45) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
Phosphoric Acid SCHEMBL5808534 0.94 CYP1A2 (0.45) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL5807565 0.93 CYP1A2 (0.44) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
Nitric Acid SCHEMBL5806212 0.92 CYP3A4 (0.43) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
Trifluoroacetic Acid SCHEMBL5806964 0.91 CYP1A2 (0.43) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
Hydrochloric Acid SCHEMBL5810732 0.88 CYP1A2 (0.39) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL5810880 0.88 HTR6 (0.43) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL5806790 0.88 CYP1A2 (0.51) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
Hydrochloric Acid SCHEMBL5809447 0.87 CYP1A2 (0.50) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006025717-A1 PYRROLO[2,3-c]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF YUHAN CORPORATION (KR) 2006-03-09 WO claimed
WO-2006025717-A1 PYRROLO[2,3-c]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF YUHAN CORPORATION (KR) 2006-03-09 WO disclosed