Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RUNX1 | Q01196 | 7/20 | 0.56 |
| ▸ | CBFB | Q13951 | 3/20 | 0.56 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.56 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.53 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.51 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.49 |
| ▸ | KIF11 | P52732 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5807225 | 0.81 | SCN10A (0.56) | RUNX1CBFBTRPV1SCN10AEGLN1 | |
| SCHEMBL13219327 | 0.81 | RUNX1 (0.56) | RUNX1CBFBTRPV1SCN10AEGLN1 | |
| SCHEMBL32674484 | 0.81 | RUNX1 (0.56) | RUNX1CBFBTRPV1SCN10AEGLN1 | |
| SCHEMBL2108297 | 0.81 | RUNX1 (0.56) | RUNX1CBFBTRPV1SCN10AEGLN1 | |
| SCHEMBL10146526 | 0.81 | TRPV1 (0.59) | RUNX1CBFBTRPV1SCN10AEGLN1 | |
| SCHEMBL9674405 | 0.81 | KDM4E (0.58) | RUNX1CBFBTRPV1SCN10AEGLN1 | |
| SCHEMBL18190875 | 0.81 | RUNX1 (0.56) | RUNX1CBFBTRPV1SCN10AEGLN1 | |
| SCHEMBL11903493 | 0.80 | RUNX1 (0.58) | RUNX1CBFBTRPV1SCN10AEGLN1 | |
| Hydrochloric Acid SCHEMBL9765815 | 0.79 | SCN10A (0.55) | RUNX1CBFBTRPV1SCN10AEGLN1 | |
| SCHEMBL3639932 | 0.79 | RUNX1 (0.59) | RUNX1CBFBTRPV1SCN10AEGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006050148-A2 | PROPARGYL TRIFLUOROMETHOXY AMINOBENZIMIDAZOLE DERIVATIVES | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 2006-05-11 | — | — | WO | disclosed |