Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4717441 | 0.82 | CA1 (0.35) | ALDH1A1KMT2AHSD17B10POLB | |
| SCHEMBL28394201 | 0.82 | CA1 (0.35) | ALDH1A1KMT2AHSD17B10POLB | |
| SCHEMBL2251329 | 0.82 | CA1 (0.35) | ALDH1A1KMT2AHSD17B10POLB | |
| SCHEMBL2254566 | 0.82 | CA1 (0.35) | ALDH1A1KMT2AHSD17B10POLB | |
| SCHEMBL16015284 | 0.75 | LMNA (0.39) | CYP1A2TDP1LMNAKDM4EHRH3 | |
| N-Methylpiperidine SCHEMBL11878290 | 0.75 | LMNA (0.39) | CYP1A2TDP1LMNAKDM4EHRH3 | |
| SCHEMBL6238723 | 0.75 | LMNA (0.39) | CYP1A2TDP1LMNAKDM4EHRH3 | |
| SCHEMBL17771605 | 0.75 | LMNA (0.39) | CYP1A2TDP1LMNAKDM4EHRH3 | |
| SCHEMBL19677596 | 0.72 | LMNA (0.43) | CYP1A2TDP1LMNAKMT2AKDM4E | |
| SCHEMBL3793955 | 0.71 | HRH3 (0.37) | CYP1A2TDP1LMNAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006024841-A2 | BENZAMIDE COMPOUNDS | ASTRAZENECA AB (SE) | 2006-03-09 | — | — | WO | claimed |