Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.31 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.31 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4675704 | 0.74 | EPHX1 (0.33) | SIGMAR1CTSLPPARGTAAR1EPHX1 | |
| SCHEMBL27469602 | 0.73 | GRIN2B (0.41) | GRIN2BKDM1A | |
| SCHEMBL10979780 | 0.71 | SIGMAR1 (0.34) | SIGMAR1CTSLMMP8PPARGTAAR1 | |
| SCHEMBL15848206 | 0.71 | EPHX1 (0.44) | SIGMAR1TAAR1SLC18A2EPHX1 | |
| SCHEMBL497585 | 0.69 | SIGMAR1 (0.46) | SIGMAR1TAAR1SLC18A2 | |
| SCHEMBL10403496 | 0.68 | EPHX1 (0.41) | SIGMAR1TAAR1EPHX1 | |
| SCHEMBL2452705 | 0.68 | CYP1A2 (0.34) | CTSLMMP8PPARG | |
| Hydrochloric Acid SCHEMBL28154419 | 0.66 | NPC1 (0.38) | MAPT | |
| SCHEMBL4244385 | 0.65 | EPHX1 (0.40) | SIGMAR1TAAR1EPHX1 | |
| SCHEMBL11451574 | 0.65 | MEN1 (0.45) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006093518-A2 | THIENYL COMPOUNDS FOR TREATING VIRUS-RELATED CONDITIONS | APATH, LLC (US) | 2006-09-08 | — | — | WO | disclosed |