Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.35 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6336580 | 0.72 | CCNB2 (0.46) | L3MBTL1KCNH3SGMS2TSHRMEN1 | |
| SCHEMBL14335707 | 0.72 | TSHR (0.42) | L3MBTL1TSHRNPSR1KCNN4HSD17B10 | |
| SCHEMBL11221104 | 0.72 | TSHR (0.42) | L3MBTL1TSHRNPSR1KCNN4HSD17B10 | |
| SCHEMBL11081209 | 0.70 | TSHR (0.40) | L3MBTL1TSHRNPSR1KCNN4HSD17B10 | |
| SCHEMBL583081 | 0.70 | CCNE2 (0.44) | L3MBTL1TSHRKMT2ANPSR1KCNN4 | |
| SCHEMBL5698837 | 0.69 | GAA (0.43) | KCNH3NPSR1ALDH1A1CYP2C19 | |
| SCHEMBL29278692 | 0.68 | TDP1 (0.39) | L3MBTL1TSHRNPSR1KCNN4HSD17B10 | |
| Ammonia Solution, Strong SCHEMBL9367371 | 0.68 | TSHR (0.39) | L3MBTL1PDE4ATSHRNPSR1KCNN4 | |
| Hydrochloric Acid SCHEMBL17710397 | 0.68 | CCNE2 (0.42) | L3MBTL1TSHRKMT2ANPSR1KCNN4 | |
| SCHEMBL9399546 | 0.68 | GAA (0.41) | TSHRKMT2ANPSR1HSD17B10CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644325-A2 | METHODS AND COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES | Neurochem (International) Limited (CH) | 2006-04-12 | — | — | EP | disclosed |
| WO-2004113275-A2 | METHODS AND COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES | NEUROCHEM (INTERNATIONAL) LIMITED (CH) | 2004-12-29 | — | — | WO | disclosed |