Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.37 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2640783 | 0.80 | GAA (0.41) | GAAALOX12CYP2C19MAPTNPSR1 | |
| SCHEMBL7204796 | 0.79 | CLCN2 (0.38) | GAAMAPTKMT2A | |
| SCHEMBL6007829 | 0.78 | RAB9A (0.39) | GAAALOX12CYP2C19MAPTTSHR | |
| SCHEMBL8433637 | 0.77 | TDP1 (0.39) | ALOX12CYP2C19MAPTNPSR1IDO1 | |
| SCHEMBL9879385 | 0.77 | KCNN4 (0.41) | GAAALOX12CYP2C19MAPTKMT2A | |
| Hydrochloric Acid SCHEMBL28538903 | 0.77 | GAA (0.38) | GAAALOX12CYP2C19MAPTNPSR1 | |
| SCHEMBL11221104 | 0.76 | TSHR (0.42) | ALOX12CYP2C19MAPTNPSR1IDO1 | |
| SCHEMBL14335707 | 0.76 | TSHR (0.42) | GAAALOX12CYP2C19MAPTNPSR1 | |
| SCHEMBL583081 | 0.74 | CCNE2 (0.44) | ALOX12MAPTNPSR1TSHRKMT2A | |
| SCHEMBL11081209 | 0.74 | TSHR (0.40) | GAAALOX12MAPTNPSR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5369030-A | Method of inducing cellular differentiations and altering cell phenotype using ceramide analogs | DUKE UNIVERSITY (US) | 1994-11-29 | — | — | US | disclosed |
| US-4666453-A | Nitro-meta-phenylenediamines halogenated in the 6th position and their use in dyeing keratinic substances | L'OREAL (FR) | 1987-05-19 | — | — | US | disclosed |
| US-3932612-A | Insecticidal compositions for sustained release of 0,0-dimethyl-0-(2,2-dichlorovinyl) phosphate | BAYER AKTIENGESELLSCHAFT (DT) | 1976-01-13 | — | — | US | disclosed |