Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.70 |
| ▸ | TSHR | P16473 | 2/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | PKM | P14618 | 1/20 | 0.66 |
| ▸ | CTNNB1 | P35222 | 10/20 | 0.64 |
| ▸ | WNT3A | P56704 | 6/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.57 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.57 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4258312 | 0.89 | CTNNB1 (0.64) | ATMHPGDCTNNB1WNT3AKDM4E | |
| SCHEMBL653025 | 0.85 | PKM (0.87) | ATMTSHRHPGDPKMCTNNB1 | |
| SCHEMBL4831672 | 0.84 | ATM (0.72) | ATMTSHRHPGDPKMCTNNB1 | |
| SCHEMBL1535157 | 0.84 | ATM (0.72) | ATMTSHRHPGDPKMCTNNB1 | |
| SCHEMBL7791783 | 0.82 | ATM (0.70) | ATMTSHRHPGDPKMCTNNB1 | |
| SCHEMBL13785039 | 0.82 | ATM (0.70) | ATMTSHRHPGDPKMCTNNB1 | |
| SCHEMBL13715357 | 0.82 | ATM (0.70) | ATMTSHRHPGDPKMCTNNB1 | |
| SCHEMBL627847 | 0.82 | ATM (0.70) | ATMTSHRHPGDPKMCTNNB1 | |
| SCHEMBL5370469 | 0.82 | ATM (0.70) | ATMTSHRHPGDPKMCTNNB1 | |
| SCHEMBL2840339 | 0.82 | ATM (0.70) | ATMTSHRHPGDPKMCTNNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006093518-A2 | THIENYL COMPOUNDS FOR TREATING VIRUS-RELATED CONDITIONS | APATH, LLC (US) | 2006-09-08 | — | — | WO | disclosed |