Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 13/20 | 0.55 |
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8258867 | 1.00 | HDAC1 (0.55) | HDAC1USP30HDAC8 | |
| SCHEMBL8260313 | 0.91 | HDAC1 (0.56) | HDAC1 | |
| SCHEMBL8260475 | 0.87 | HDAC1 (0.52) | HDAC1 | |
| SCHEMBL5810811 | 0.87 | HDAC1 (0.52) | HDAC1 | |
| SCHEMBL8258865 | 0.86 | HDAC1 (0.56) | HDAC1USP30 | |
| SCHEMBL5809254 | 0.86 | HDAC1 (0.56) | HDAC1USP30 | |
| SCHEMBL8260770 | 0.86 | HDAC1 (0.63) | HDAC1HDAC8 | |
| SCHEMBL5806240 | 0.85 | HDAC1 (0.53) | HDAC1 | |
| SCHEMBL8258575 | 0.85 | HDAC1 (0.53) | HDAC1 | |
| SCHEMBL8255855 | 0.85 | HDAC1 (0.61) | HDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006101454-A1 | BENZOTHIOPHENE DERIVATIVES: PREPARATION AND PHARMACEUTICAL APPLICATIONS | S*BIO PTE LTD (SG) | 2006-09-28 | — | — | WO | claimed |