Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 13/20 | 1.00 |
| ▸ | TUBB | P07437 | 13/20 | 1.00 |
| ▸ | TUBA3C | P0DPH7 | 13/20 | 1.00 |
| ▸ | TUBA1B | P68363 | 13/20 | 1.00 |
| ▸ | TUBA4A | P68366 | 13/20 | 1.00 |
| ▸ | TUBB4B | P68371 | 13/20 | 1.00 |
| ▸ | TUBB3 | Q13509 | 13/20 | 1.00 |
| ▸ | TUBB2A | Q13885 | 13/20 | 1.00 |
| ▸ | TUBB8 | Q3ZCM7 | 13/20 | 1.00 |
| ▸ | TUBA3E | Q6PEY2 | 13/20 | 1.00 |
| ▸ | TUBA1A | Q71U36 | 13/20 | 1.00 |
| ▸ | TUBA1C | Q9BQE3 | 13/20 | 1.00 |
| ▸ | TUBB6 | Q9BUF5 | 13/20 | 1.00 |
| ▸ | TUBB2B | Q9BVA1 | 13/20 | 1.00 |
| ▸ | TUBB1 | Q9H4B7 | 13/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | HTR6 | P50406 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22802275 | 0.90 | TUBB4A (0.82) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL5813055 | 0.89 | TUBB4A (0.80) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL25761908 | 0.88 | TUBB4A (0.78) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL5812479 | 0.86 | TUBB4A (0.75) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL8938353 | 0.86 | TUBB4A (0.74) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL21465493 | 0.86 | TUBB4A (0.74) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL21465547 | 0.86 | TUBB4A (0.74) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL7672368 | 0.85 | TUBB4A (0.74) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL5798445 | 0.85 | TUBB4A (1.00) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL5813513 | 0.84 | TUBB4A (0.72) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103288707-B | A kind of preparation method of 3-benzene sulfydryl indole derivative | ZHEJIANG UNIVERSITY (CN) | 2015-12-23 | — | — | CN | disclosed |
| CN-103288707-A | Preparation method of 3-sulfinyl indole derivative | UNIV ZHEJIANG | 2013-09-11 | — | — | CN | disclosed |
| WO-2006041961-A1 | ARYLTHIOINDOLE TUBULIN POLYMERIZATION INHIBITORS AND METHODS OF TREATING OR PREVENTING CANCER USING SAME | GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTHAND HUMAN SERVICES (US) | 2006-04-20 | — | — | WO | disclosed |